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  [essays and dissertation][Other Subjects][Other Science and Technology]Investigation of a liquid–liquid extraction system based on non-ionic surfactant–salt–H2O and mechanism of drug extraction论文



论文编号: lw200708151152124104
论文属性: Courswork
论文语言:English
论文国家:China
登出日期: 2007-08-15  
字数: 4000
源程序: 无
价格: 100
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关键词搜索:Investigation   liquid–liquid extraction system    mechanism of drug extraction   
 
Investigation of a liquid–liquid extraction system based on non-ionic surfactant–salt–H2O and mechanism of drug extraction

Abstract
Based on the investigation of a non-ionic surfactant–salt–H2O liquid–liquid extraction system, general rules concerning
salt selection are concluded and the mechanism of phase separation is explained. The extraction behavior of chlorpromazine
hydrochloride (CPZ) and procaine hydrochloride (PCN) in such a system is studied. Research shows that the extraction
efficiency of CPZ can amount to 96% by twice extraction, which means that quantitative extraction is realized, while that of
PCN is 77%. This system produces distribution coefficients (KD) of 12.3 and 2.6, respectively, for CPZ and PCN. Extraction
mechanism is deduced according to ultraviolet absorbance; and molecular fluorescence spectra change of the drugs in the
system studied. © 2002 Elsevier Science B.V. All rights reserved.
Keywords: Non-ionic surfactant–salt–H2O extraction system; Polyethylene glycol-1000; Chlorpromazine hydrochloride; Procaine
hydrochloride; Mechanism of extraction英语论文网 【http://www.51lunwen.org】 本文来自:英语论文网 【http://www.51lunwen.org】
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