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美国留学生本科论文范文：产后抑郁症

抗抑郁药是一种安全的、有效的治疗产后抑郁症的药物?

本文评估了有关抗抑郁药物的安全性和有效性，以证明其对产后抑郁症的恢复确实有效。这将为产后抑郁症患者进行治疗时候的临床决策提供了充分的证据。这些数据来自多个雅典的电子和免费数据库，这些数据库涉及到精神生物医学和和护理文献。

研究包括随机临床试验、案例和同期组群对照研究,问卷调查和定性/探索性研究。先前的评论也得到有效地评估。结果显示，超过1200个母亲、母婴的配对或婴儿,都与抗抑郁药有关。抗抑郁药似乎能够明显缓解抑郁症状。此外,报告显示的副作用通常是良性的,临床上微不足道。然而,方法论和分析缺陷否定结论性的推论。

许多研究没有考虑到重要的协变量,这些可以解释抗抑郁药所带来的影响。此外,大多数研究没有考虑到抗抑郁药物和患者之间的相互作用,而这些恰恰可以揭示更多严重的不利影响。此外,从长期影响来看，缺乏文献支撑。最后,缺乏随机临床试验排除了因果关系的推论。考虑到这些限制建议，抗抑郁药物的使用被作为最后的手段,密切监测病人的病况以识别意想不到的副作用,这些可能是协变量引起的,而不是抗抑郁药。

Antidepressants are they a safe and effective choice for the treatment of postnatal depression?

This review assessed the evidence concerning the effectiveness and safety of antidepressants in the management of postnatal depression. This would facilitate evidence-based clinical decisions in the treatment of patients. Data was sourced from several electronic Athens-based and free databases covering the psycho-biomedical and nursing literature.

Studies found included randomised clinical trials, case- and cohort-controlled studies, questionnaire surveys, and qualitative/exploratory research. Previous reviews were also appraised. Outcomes from over 1200 mothers, mother-infant pairings, or infants, exposed to antidepressants were considered. Antidepressants appear to significantly alleviate depressive symptoms. Furthermore, the reported side effects are generally benign and clinically insignificant. However, methodological and analytic flaws negate conclusive inferences.

Many studies fail to account for important covariates that may explain effects attributed to antidepressants. Furthermore, most studies fail to account for interactions between antidepressants and patient characteristics, which may reveal more severe adverse effects. Additionally, there is a paucity of literature on long-term effects. Finally, a lack of randomised clinical trials precludes inferences of causality. Given these constraints it is recommended that antidepressants are used as a last resort, and patients are closely monitored to identify unexpected side effects, or recovery induced by covariates rather than antidepressants.

Chapter One

Introduction, Rationale, AIMS

Introduction

According to Beckford-ball (2000) postnatal depression (PND) fails to attract public attention because it is associated with a positive event – childbirth – notwithstanding the evidence that a sizeable majority of women experience this phenomenon after delivering their baby (RCP , 2004). Nevertheless postnatal depression, if left untreated, can have adverse effects for mother-child relationship and infant development (Green, 1995).

This brief reviews evidence concerning the safety and effectiveness of antidepressants for treating postnatal depression. It is argued that while antidepressants may alleviate depressive symptoms, with benign side effects, various methodological and analytic constraints in the literature negate conclusive inferences on the subject. 本论文由英语论文网提供整理，提供论文代写，英语论文代写，代写论文，代写英语论文，代写留学生论文，代写英文论文，留学生论文代写相关核心关键词搜索。