英语论文网

rediction 2: do manipulations that increase lifespan reduce the age-related increase in oxidativelydamaged biomolecules?
4.1. Caloric restrictio4.2. Genetic manipulations
4.2.1. C. elegans
4.2.2. Drosophila
4.2.3. Mice
5. Prediction 3: do manipulations that alter ROSproduction, ROS scavenging, or turnover/repairprocesses alter life span/aging?
6. Discussion
7. Epilogue


Acknowledgements


References


Adachi, H., Fujiwara, Y., Ishii, N., 1998. Effects of oxygen on proteincarbonyland aging in Caenorhabditis elegans mutants with long (age-1)and short (mev-1) life spans. J. Gerontol. 53, B240–B244.Agarwal, S., Sohal, R.S., 1993. Relationship between aging and suscept-ibility to protein oxidative damage. Biochem. Biophys. Res. Commun.194, 1203–1206.Aksenova, M.V., Aksenov, M.Y., Carney, J.M., Butterfield, D.A., 1998.Protein oxidation and enzyme activity decline in old brown Norway ratsare reduced by dietary restriction. Mech. Ageing Dev. 100, 157–168.Ames, B.N., Shigenaga, M.K., Hagen, T.M., 1993. Oxidants, antioxidants,and the degenerativediseases of aging.Proc. Natl. Acad.Sci. U.S.A.90,7915–7922.Amin, J.K., Xiao, L., Pimental, D.R., Pagano, P.J., Singh, K., Sawyer, D.B.,Colucci, W.S., 2001. Reactive oxygen species mediate alpha-adrenergicreceptor-stimulated hypertrophy in adult rat ventricular myocytes. J.Mol. Cell. Cardiol. 33, 131–139.Anson, R.M., Senturker, S., Dizdaroglu, M., Bohr, V.A., 1999. Measure-ment of oxidatively induced base lesions in liver from Wistar rats ofdifferent ages. Free Radic. Biol. Med. 27, 456–462.A. Bokov et al./Mechanisms of Ageing and Development 125 (2004) 811–826821Arking,R.,Burde,V.,Graves,K.,Hari,R.,Feldman,E.,Zeevi,A.,Soliman,S., Saraiya, A., Buck, S., Vettraino, J., Sathrasala, K., 2000a. Identicallongevity phenotypes are characterized by different patterns of geneexpression and oxidative damage. Exp. Gerontol. 35, 353–373.Arking,R.,Burde,V.,Graves,K.,Hari,R.,Feldman,E.,Zeevi,A.,Soliman,S., Saraiya, A., Buck, S., Vettraino, J., Sathrasala, K., 2000b. Identicallongevity phenotypes are characterized by different patterns of geneexpression and oxidative damage. Exp. Gerontol. 35, 353–373.Arking,R.,Burde,V.,Graves,K.,Hari,R.,Feldman,E.,Zeevi,A.,Soliman,S., Saraiya, A., Buck, S., Vettraino, J., Sathrasala, K., Wehr, N., Levine,R.L., 2000c. Forward and reverse selection for longevity in Drosophilais characterized by alteration of antioxidant gene expression andoxidative damage patterns. Exp. Gerontol. 35, 167–185.Arking, R., Dudas, S.P., Baker III, G.T., 1993. Genetic and environmentalfactors regulating the expression of an extended longevity phenotype ina long lived strain of Drosophila. Genetica 91, 127–142.Armstrong, R.C., Swallow, A.J., 1969. Pulse- and gamma-radiolysis ofaqueous solutions of tryptophan. Radiat. Res. 40, 563–579.Asahi, T., Bandurski, R.S., Wilson, L.G., 1961. Yeast sulfate-reducingsystem. II. Enzymatic reduction of protein disulfide. J. Biol. Chem.236, 1830–1835.Baboolal, H.A., Ichinose, F., Ullrich, R., Kawai, N., Bloch, K.D., Zapol,W.M., 2002. Reactive oxygen species scavengers attenuate endotoxin-induced impairment of hypoxic pulmonary vasoconstriction in mice.Anesthesiology 97, 1227–1233.Barsyte,D.,Lovejoy,D.A.,Lithgow,G.J.,2001.Longevityandheavymetalresistance in daf-2 and age-1 long-lived mutants of Caenorhabditiselegans. FASEB J. 15, 627–634.Bartke,A., Brown-Borg, H., Mattison,J., Kin本论文由英语论文网提供整理，提供论文代写，英语论文代写，代写论文，代写英语论文，代写留学生论文，代写英文论文，留学生论文代写相关核心关键词搜索。