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论文作者:www.51lunwen.org论文属性:本科毕业论文 Thesis登出时间:2014-08-12编辑:felicia点击率:27406
论文字数:11857论文编号:org201408120838054271语种:英语 English地区:中国价格:免费论文
关键词:抗抑郁药安全性有效性Antidepressantseffectivesafe
摘要:本文是一篇美国留学论文,文章主要研究抗抑郁药治疗效果以及产后抑郁症。抗抑郁药是一种安全的、有效的治疗产后抑郁症的药物吗?本文主要评估了有关抗抑郁药物的安全性和有效性,以证明其对产后抑郁症的恢复确实有效。通过一些数据和文献提供充分的证据以表明抗抑郁药对于治疗产后抑郁症有一定的效果。
Only a 16% of units provided midwifes with specific training in screening women for depression.
Midwifes and their colleagues reported a number of problems encountered including difficulties accessing referral services (some clinical consultants would not accept midwifery referrals) and lack of adequate training. The current review suggests that it is essential that midwifes receive the necessary training and support to effectively screen women for PND, and hence identify the more severe cases that may require antidepressants.
Furthermore, given the paucity of studies accounting for important confounding variables, it is essential that midwifes obtain comprehensive background information from each patient – this would provide an essential database to facilitate further randomised clinical trials and cohort/case-controlled studies which account for key covariates in testing assessing the efficacy and safety of antidepressants.
Final word
Scientific research findings are never conclusive. Even well designed clinical trials often raise more questions than they address. Empirical literature suggests that antidepressants, notably SSRIs and TCAs, can be effective in treating PND, with side effects that are mostly benign. However, the evidence is plagued by various methodological and analytic constraints, so that any conclusions reached are highly tentative at best.
Thus, caution is advised in the use of antidepressants: consistent with national guidelines on the treatment of depression(e.g. DOH, 2004; NICE, 2004), it is recommended that antidepressants are not used unless PND symptoms are judged to be severe.
Ultimately literature reviews such as this one can be highly subjective in the evaluation of studies and interpretation of findings. Thus, there is need for meta-analytic reviews, which take account of methodological and statistical factors in each study and report effect sizes. This would provide a more accurate estimate of the clinical benefits of antidepressants and the seriousness of any side effects.
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