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腹腔镜技术在II型糖尿病中的应用

论文作者:www.51lunwen.org论文属性:作业 Assignment登出时间:2013-09-17编辑:holy980点击率:6581

论文字数:1302论文编号:org201309031944303455语种:英语 English地区:中国价格:免费论文

关键词:医学研究医疗技术新医疗手段

摘要:II型糖尿病(T2DM)是一种常见的难以根治的慢性病,传统药物和胰岛素治疗的目标只是维持正常血糖水平,患者需要终生用药。糖尿病外科手术的目标是让T2DM 患者在不再用药和不再饮食控制的情况下,术后血糖得以终生维持在正常水平。

糖尿病是一组以慢性血葡萄糖(简称血糖)水平升高为特征的代谢性疾病,是由于胰岛素分泌和作用缺陷引起的。其中以II型糖尿病最为多见,约占糖尿病的90%以上,其基本病因为: 胰岛素分泌受损和胰岛素抵抗。


   Diabetes is a group of chronic blood glucose (sugar short) is characterized by elevated levels of metabolic disease which is due to insulin secretion and action defects. Among them, Type II diabetes is the most common, accounting for more than 90% of diabetes, its basic disease because of: impaired insulin secretion and insulin resistance. "Chinese Hypertension Prevention Guide" states: 2002 residents over the age of 18 diabetes incidence rate of 2.6%, impaired fasting glucose was 1.9%. Estimated number of diabetics over 22 million, in addition to approximately 16 million people with impaired fasting glucose. Compared with 1996, aged 20 and over in the big cities diabetes prevalence rate of 4.6% up to 6.4%, up 39%. Country from 1980 to 1995 the incidence of diabetes has increased by nearly 2.5 times. This data is easy to see our work in the fight against diabetes requires the majority of doctors go all out. In addition, according to the latest data show that in the world of type II diabetes has more than 150 million people, China has more than 40 million, which become, after cardiovascular disease and cancer, the third largest non-communicable diseases. Currently the treatment of diabetes mainly taken early, long-term, proactive, personalized conservative treatment, unable to take radical treatment. In recent years as foreign adoption continuing reports of laparoscopic treatment of diabetes, which caused widespread concern at home and abroad GPs, diabetes has become another major leap forward. 


1. Pathophysiology of type II diabetes: 


II型糖尿病的发病机制主要包括胰岛β细胞功能受损和胰岛素抵抗. II型糖尿病是"自身胰岛素抵抗为主伴胰岛素相对不足至胰岛素分泌缺陷为主伴胰岛素抵抗"的一类糖尿病.对II型糖尿病高危人群的前瞻性调查显示在葡萄糖耐量受损之前他们已经有胰岛素抵抗和胰岛素分泌的缺陷.


   The pathogenesis of type II diabetes include islet β cell dysfunction and insulin resistance. II diabetes is "self insulin resistance with relative insulin deficiency mainly to defects in insulin secretion, insulin resistance mainly" a class of diabetes type II high risk of diabetes in a prospective survey showed impaired glucose tolerance before they have insulin resistance and insulin secretion defects. So, now reduced insulin sensitivity or insulin secretion is the primary factor in Type II diabetes is still controversial. many studies evidence that type II diabetes is a heterogeneous disease, pancreatic β cell dysfunction is a major congenital factors, and IR is acquired factor in pancreatic β cell dysfunction, based on coupled IR leads to tolerance damaged or type II diabetes. 

2 laparoscopic surgical methods for treating diabetes: 


首例报道是温州医学院第一附属医院腔镜外科于2009年3月30日用腹腔镜DJB治疗T2DM。手术的主要步骤:自幽门下2 cm用切割吻合器离断十二指肠起始部;自屈氏韧带以下30 cm处用切割吻合器离断空肠。


   The first report of the First Affiliated Hospital of Wenzhou Medical College, laparoscopic surgery March 30, 2009 Daily laparoscopic DJB treatment T2DM. Surgical main steps: from 2 cm below the pylorus by cutting stapler transection beginning part of the duodenum; since 30 cm below the ligament of Treitz at a cutter stapler transection jejunum; proximal ends of the jejunal anastomosis to empty heartbroken about 50 cm at the end of the following; distal ends of the jejun论文英语论文网提供整理,提供论文代写英语论文代写代写论文代写英语论文代写留学生论文代写英文论文留学生论文代写相关核心关键词搜索。

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